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About this paper

Andreas Motzfeldt, Joakim Edin, Casper L. Christensen, Christian Hardmeier, Lars Maaløe, Anna Rogers

Corti.ai researchers introduce "Code Like Humans" (CLH), a multi-agent, LLM-based framework that mimics human medical coding workflows to handle the full US ICD-10-CM system with over 70,000 labels. This approach, leveraging external ICD resources, demonstrates improved performance on rare codes and establishes a new baseline for full-scale medical coding.

Key insights

  • Emulating human multi-step reasoning and explicitly integrating external knowledge resources through an agentic LLM framework is crucial for addressing the full complexity of medical coding beyond constrained label spaces.
  • Enriching LLM input context with structured guideline information and employing 'thinking-enabled' decoding significantly enhances agent performance, especially for refining and validating candidate codes.
  • Performance analysis reveals specific 'blind spots' of the system, such as abbreviations, social qualifiers, and psychological terms, highlighting areas for future targeted improvements in LLM reasoning abilities.

Summary by alphaXiv.

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