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About this paper

Ekin Ince, Murat Kuscu

The authors propose non-genetic cell surface engineering as a fourth paradigm for the Internet of Bio-Nano Things (IoBNT), attaching synthetic molecular functions to living cells without changing their genes. They synthesize prior demonstrations of cell-surface logic and behavior control, then envision red-blood-cell sentinels and an in-vitro computer. These architectures remain proposals, with cell agency and finite surface-function lifetimes unresolved.

Summary by alphaXiv.

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