Reproduce “CountsDiff: A Diffusion Model on the Natural Numbers for Generation and Imputation of Count-Based Data” on OpenResearch

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About this paper

Renzo G. Soatto, Anders Hoel, Greycen Ren, Shorna Alam, Stephen Bates, Nikolaos P. Daskalakis, Caroline Uhler, Maria Skoularidou

CountsDiff models natural-number counts by removing units and learning to restore them; reverse steps can also remove units. In a synthetic sparse-count test, it better matches the target than Gaussian and masked categorical diffusion. For fetal-cell-atlas imputation at 50% MCAR, its SWD is 0.08 (SE 0.01), versus ReMDM’s 0.12 (SE 0.01); this is not a general robustness claim.

Key insights

  • Directly modeling count data on natural numbers with a pure-death process and binomial marginals offers a more appropriate and efficient generative approach compared to continuous or categorical relaxations.
  • Integrating advanced diffusion features like attrition (allowing non-monotonic count changes) and classifier-free guidance significantly enhances sample quality, robustness, and control in count-based data generation and imputation.
  • A reparameterized p-schedule within a continuous-time framework for count-based diffusion allows for stable training and effective transfer of noise schedule designs from well-established Gaussian diffusion models.

Summary by alphaXiv.

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