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About this paper

Rahul Thapa, Christopher Sun, William Theodor Lehn-Schioler, Sophia Claire Kivelson, Umaer Hanif, Hyatt Moore IV, Harrison G. Zhang, Hafsa Ahmed and 9 more

SleepFM-2 uses a frozen model trained on overnight polysomnography to combine brain, eye, heart, muscle, breathing and oxygen signals for clinical prediction. It represents one-second channel patches jointly, then task-specific heads reuse that representation. It identified 188 incident diagnoses meeting the authors’ criteria in both cohorts, including an unseen health system; these retrospective risk rankings do not establish disease onset.

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