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About this paper
Antonio Scardace, Silvia Ingala, Sebastiano Battiato, Daniele Ravì
MC-LDM forecasts future 3D brain MRI using multimodal measurements available during training without requiring future tau-PET or clinical ratings at inference. It estimates future tau uptake and Clinical Dementia Rating from baseline information, while anchoring anatomy to baseline MRI. On the ADNI test set, lateral-ventricle volumetric MAE was 0.291 ± 0.279% versus BrLP’s 0.407 ± 0.444%; this is not external validation.
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