Reproduce “EPC-RawDC: Equivariant Physics Constrained 3D Diffusion with Raw Data Consistency for CBCT to CT Image Synthesis” on OpenResearch

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About this paper

Alzahra Altalib, Chunhui Li, Alessandro Perelli

EPC-RawDC combines scan-specific CBCT projection measurements with geometry-transformed reference projections to supervise a three-dimensional diffusion model that produces synthetic CT from CBCT. Through a scanner-specific forward model, it compares predicted projections with both sources. On 24 SynthRAD2025 patients, mean PSNR was 39.18 dB versus 36.52 for DDPM; these projections were simulated, and dose-calculation benefit remains untested.

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