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About this paper

Weida Wang, Benteng Chen, Yigeng Jiang, Shuchen Pu, Weiping Shen, Zichao Liu, Yulin Su, Zitong Wang and 82 more

The authors present Sage-Taiyi, a research system that tracks evidence, assumptions, uncertainty, and scope to guide which targets and reasoning methods to pursue. In expert-guided cobalt-catalyzed carbonylation, condition optimization raised isolated yield from trace to 84%. On Taiyi-Bench, Sage-Taiyi scored 53.95 versus 47.85 for AI Scientist-v2; this full-system comparison does not isolate monitoring’s contribution.

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